Animal MRI Research

Senior Scientist: Prof Gary Egan

Group members: Dr. Zhaolin Chen, Dr. Hong Wang, Scott Kolbe, David Wright, Jing Gu


3D MR Image of the Hippocampus in normal and Huntington's disease mice

Florey Neurosciences MRI Facility

 

MRI is an essential experimental technique for the non-invasive study of animal models of neurological, vascular and oncological disease.

Researchers in the Animal MRI are developing and applying methods for imaging the structure and function of the brain. These techniques will be used to image normal and abnormal brain development and the evolution of disordered connectivity resulting from neurological disorders and brain injury.

 

Applications currently being used include:
Diffusion tensor imaging,
Diffusion weighted imaging,
MR tractography,
Manganese Enhanced MR imaging,
Contrast Agent MR imaging,
BOLD imaging,
Spectroscopy, and
Arterial Spin Labelling

Clinical Investigations include:
Epilepsy,
Stroke,
Huntington’s disease,
Parkinson’s disease,
Multiple Sclerosis, and
Traumatic Brain Injury.

Australian Mouse Brain Mapping Consortium
Established in 2006 (funded by an NHMRC Enabling Grant) the Consortium aims to develop the next generation of probabilistic mouse brain atlases incorporating both MR and histochemical information. The Animal MRI Research group will contribute imaging expertise to this ongoing national collaboration.

Available Student Projects:
Manganese MRI